Synthesis of Cyclic Guanidines Fused with Aromatic Ring through Metal Ion Promoted Cyclization
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چکیده
منابع مشابه
Stereoselective synthesis of cyclopentanone-fused benzosultams through Tomita zipper cyclization.
A powerful intermolecular version of the Tomita zipper-cyclization (TZC) reaction was developed to provide functionalized drug-like cyclopentanone-fused benzosultams in good yields with excellent stereoselectivities using organophosphine-catalysis.
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The key step in the synthesis of new five, six and seven-membered alicyclic ring [1,2-a]-fused bioreductive benzimidazolequinones was radical cyclisation. Six and seven-membered tributyltin hydride-mediated homolytic aromatic substitutions of nucleophilic N-alkyl radicals onto the benzimidazole-2-position occurred in high yields (63-70 %) when quaternising the pyridine-like 3-N of imidazole wit...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1983
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.56.3189